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High Purity Pharmaceutical Raw Material Niraparib Tosylate CAS 1613220-15-7 MK-4827

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  • Casno:1613220-15-7 - LookChem

    goodquality and high purity Niraparib tosylate CAS NO.1613220-15-7. Min.Order: 1 Kilogram FOB Price: USD 1000.0-1000.0/Kilogram production description Appearance:white power Storage:Keep away from sunlight, sealed in dry place Package:1kg/bag, 25kg/drum Application:It is an important raw material and intermediate for chemical industry Transportation:By Express, By Air,

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  • Niraparib HCl | MK-4827 | CAS#1038915-64-8 | PARP ...

    Niraparib, also know as MK-4827, is a n inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway.

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    API Paclitaxel taxol intermediate of paclitaxel 33069-62-4 with lowest price raw material Yew Bark Extract for Ovarian cancer. US 1.00-50.00 ... treat ovarian cancer MK-4827 powder CAS 1613220-15-7 Niraparib Tosylate Monohydrate. US 10.00-300.00 Bag. 1 ... high purity raw material paclitaxel for Ovarian cancer 33069-62-4. US 67.45-69.56 ...

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  • China Lorcaserin HCL(CAS No 846589-98-8),

    Shijiazhuang Dingmin Pharmaceutical Sciences Co.,Ltd have been specialized in Lorcaserin HCL(CAS No 846589-98-8) manufacture for many years. Our main products are Enzalutamide(CAS No 915087-33-1) , Brexpiprazole(CAS No 913611-97-9),etc.

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  • Uncategorized « New Drug Approvals « Page 25

    MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1. IC50 value: 3.8 nM/2.1 nM( PARP1/2) [1] Target: PARP1/2

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    To a solution of 3,4-dihydro-6,7-dimethoxyisoquinoline hydrochloride (3, 3.5 g, 15.4 mmol) in cold H 2 O (20 mL) in an ice water bath, was added 3-(dimethylaminomethyl)-5-methyl-2-hexanone (2, 3.15 g, 18.3 mmol) as the free base with stirring. Precipitate formed within 3 h, and stirring was continued until the solid-gummy precipitate prevented ...

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  • EMA 2017 « New Drug Approvals

    2: Betrouni N, Lopes R, Puech P, Colin P, Mordon S. A model to estimate the outcome of prostate cancer photodynamic therapy with TOOKAD Soluble WST11. Phys Med Biol. 2011 Aug 7;56(15):4771-83. Epub 2011 Jul 13. PubMed PMID: 21753234.

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  • Casno:1613220-15-7 - LookChem

    goodquality and high purity Niraparib tosylate CAS NO.1613220-15-7. Min.Order: 1 Kilogram FOB Price: USD 1000.0-1000.0/Kilogram production description Appearance:white power Storage:Keep away from sunlight, sealed in dry place Package:1kg/bag, 25kg/drum Application:It is an important raw material and intermediate for chemical industry Transportation:By Express, By Air,

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  • Casno:1613220-15-7 - LookChem

    goodquality and high purity Niraparib tosylate CAS NO.1613220-15-7. Min.Order: 1 Kilogram FOB Price: USD 1000.0-1000.0/Kilogram production description Appearance:white power Storage:Keep away from sunlight, sealed in dry place Package:1kg/bag, 25kg/drum Application:It is an important raw material and intermediate for chemical industry Transportation:By Express, By Air,

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  • Casno:1613220-15-7 - LookChem

    goodquality and high purity Niraparib tosylate CAS NO.1613220-15-7. Min.Order: 1 Kilogram FOB Price: USD 1000.0-1000.0/Kilogram production description Appearance:white power Storage:Keep away from sunlight, sealed in dry place Package:1kg/bag, 25kg/drum Application:It is an important raw material and intermediate for chemical industry Transportation:By Express, By Air,

    Get Price