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Pharmaceutical grade diosmectite dioctahedral smectite for human

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    2018-4-25 · Dioctahedral smectite, or diosmectite, is a natural clay formed from sheets of aluminium and magnesium silicate. Its proposed mechanism of action differs from other antidiarrhoeal agents such as loperamide, which is an opioid‐receptor agonist, and racecadotril, …

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    2020-10-5 · Diosmectite was effective in all types of acute childhood diarrhoea except dysentery. Because, most of the trials were open-label, and there was a high possibility of publication bias, the GRADE evidence generated was of ‘low quality’. Conclusions Diosmectite may be a useful additive in the treatment of acute childhood diarrhoea.

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    2007-4-1 · Pharmaceutical-grade clay minerals (including smectites, kaolinite and fibrous clay minerals) have been extensively applied for prolonged release, especially of basic drugs. Smectites in particular have been the most commonly used substrates, as they can retain large amounts of drug due to their high cation exchange capacity.

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  • Montmorillonite | Al2H2O12Si4 - PubChem

    Members of the smectite group include the dioctahedral minerals montmorillonite, beidellite, and nontronite, and the trioctahedral minerals hectorite (Li-rich), saponite (Mg-rich), and sauconite (Zn-rich).The basic structural unit is a layer consisting of two inward-pointing tetrahedral sheets with a central alumina octahedral sheet.

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  • Comparative efficacy of dioctahedral smectite (Smecta

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    2020-10-5 · Diosmectite was effective in all types of acute childhood diarrhoea except dysentery. Because, most of the trials were open-label, and there was a high possibility of publication bias, the GRADE evidence generated was of ‘low quality’. Conclusions Diosmectite may be a useful additive in the treatment of acute childhood diarrhoea.

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